Retinitis Pigmentosa Society Singapore (RPSS)

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Is Retinitis Pigmentosa Associated with Other Diseases?

RP is just one type of a group of inherited diseases that causes degeneration of the Retina. Other types include rare syndromes that can usually be diagnosed at a Retinal Clinic. They are generally genetic and follow one of the 3 primary inheritance patterns. Some of these syndromes are:-

* Bardet-Biedl (Laurence-Moon) Syndrome: RP possibly accompanied by physical abnormality, obesity, kidney disease and mental retardation.
* Bassen-Kornzweig Syndrome (Abetalipoproteineinemia): RP accompanied by progressive neurological problems.
* Choroideremia: This disease has symptoms similar to Retinitis Pigmentosa but degeneration of both the Retina and the Choroid occur.
* Gyrate Atrophy: This disease is associated with a deficiency in the enzyme ornithine aminotransferase. Myopia, night blindness, cataracts and loss of peripheral vision occur.
* Leber Congenital Amaurosis: This is characterised by severe visual impairment from birth or very early childhood.
* Refsum Syndrome: This is a complex disease. Hearing loss, neurological problems, dry or flaky skin can accompany RP. Patients also have oddly shaped red blood cells.


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